Plan
Where this is going
What exists, what is being built, and what is still only an intention.
Biosphere is being built slowly and in public. This page is kept honest — if something is listed as planned, it does not exist yet.
Playable
Blackthorn: Quarantine
Microbiology survival game for BIOL 2420. Question bank, five seals, Survival and Study modes. Music is being added now.
Playable
Viral Ward: The Last Diagnosis
3D clinical-mystery game for BIOL 2420, Chapter 6 (Viruses). Examine 22 patients and name the disease, the virus and how it spread, in Learning or Challenge mode. Start your shift.
Playable
Immune League: The Blue ID Card Conspiracy
A manga sound novel for BIOL 2420 on innate and adaptive immunity. Follow Dendra, make six decisions, and listen to the included soundtrack. Begin the story.
Playable
Macromolecule Builder
Guided macromolecule lessons for BIOL 1406 and BIOL 1407, with structure identification.
Playable
Membrane Discovery Lab
Membrane permeability and diffusion for BIOL 1406 and BIOL 2420. Drag molecules across a bilayer, add transport proteins, and run diffusion experiments.
Playable
Chemical Bonding Lab
Seven guided Bohr-model stations on energy shells, covalent, polar, ionic and hydrogen bonds, and Van der Waals interactions, for BIOL 1406, BIOL 1407 and BIOL 2420.
Playable
Oxidative Phosphorylation Lab
Seven guided stations on redox reactions, proton gradients and ATP production, connecting glycolysis, the citric acid cycle and oxidative phosphorylation for BIOL 1406 and BIOL 2420.
Playable
Diffusion & Osmosis Discovery Lab
Six guided stations on diffusion, osmosis, membrane structure, transport and what happens to animal and plant cells in different solutions, for BIOL 1406 and BIOL 2420.
Playable
Microbial Metabolism Lab
Eleven guided stations on energy, enzymes, ATP, respiration and fermentation for BIOL 2420, ending with an exam check.
Playable
Eukaryote Lab
Chapter 5 review for BIOL 2420: protozoa, parasitic helminths and fungi, with clinical case files and an exam check.
Playable
Microbial Growth Lab
Chapter 9 review for BIOL 2420: doubling time, the growth curve, counting methods, biofilms, oxygen, pH, temperature and pressure, with clinical case files.
Playable
Transcription Lab
Ten guided steps for BIOL 2420 on the parts of a gene, how the promoter is found, and initiation, elongation and termination, in a eukaryote or a bacterium.
Playable
Translation Molecular Lab
A 3D ribosome for BIOL 2420: assemble at the start codon, match tRNAs to codons, form peptide bonds, translocate and release the finished chain.
Playable
Antibiotics Resistant Bacteria Simulation
Three treatment scenarios for BIOL 2420 showing how neutrophils and a full antibiotic course clear resistant and non-resistant bacteria, and what is left when the pills stop early.
Playable
Recombination Discovery Lab
Crossing over for BIOL 2420: follow two linked genes through meiosis into four gametes and see where new allele combinations come from.
Playable
Innate Defense Lab
Innate immunity for BIOL 2420, Chapter 17: the physical, mechanical, chemical and biological barriers, then inflammation from a needle stick to macrophage clean-up, linked to the cardinal signs. Open the simulation.
Playable
ConceptNavi: Energy & Enzymes
The first ConceptNavi: a guided review of Chapter 8 for BIOL 1406. Ten stations run from the laws of thermodynamics and ATP to activation energy, enzymes and their regulation, ending with a Concept Check and an Understanding Check.
Playable
ConceptNavi: DNA & DNA Replication
BIOL 2420 Unit 3A Part 1, Chapters 10–11: nine stations on genes, nucleotides, the double helix, RNA, genomes, DNA replication and telomeres, ending with a Concept Check and an Understanding Check. Open ConceptNavi.
Playable
ConceptNavi: Introduction to Anatomy & Physiology
The first ConceptNavi for BIOL 1407, Unit Exam III, Chapter 40: ten stations on form and function, tissues, nervous and endocrine signals, homeostasis and feedback, thermoregulation and energy budgets, ending with a Concept Check and an Understanding Check. Open ConceptNavi.
Playable
ConceptNavi: Cellular Respiration
BIOL 1406 Unit Exam III, Chapter 9: ten stations on redox reactions, chemiosmosis, oxidative phosphorylation, glycolysis, the citric acid cycle, the ATP tally, fermentation and metabolic control, ending with a Concept Check and an Understanding Check. Open ConceptNavi.
Playable
ConceptNavi: Photosynthesis
BIOL 1406 Unit Exam III, Chapter 10: eleven stations on light, the leaf and chloroplast, pigments, the light reactions, the Calvin cycle, and how photosynthesis and cellular respiration connect, ending with a Concept Check and an Understanding Check. Open ConceptNavi.
Playable
ConceptNavi: Chromosomes & the Cell Cycle, two parts
BIOL 1406 Unit Exam IV, Chapter 12, in two short ConceptNavi: Chromosome Basics, an Interactive Review from the DNA double helix to karyotypes, alleles and n and 2n, and Cell Cycle & Mitosis, which follows one cell through interphase and every stage of mitosis in an interactive 3D model. Each ends with a Check Yourself station.
Playable
ConceptNavi: The Process of Meiosis
BIOL 1406 Unit Exam IV, Chapter 13, Part 1: follow one cell through one round of DNA copying and two divisions in 3D, from pairing and crossing over to four haploid cells, then compare mitosis with meiosis and identify the division from drawings, ending with a Check Yourself station. Open ConceptNavi.
Playable
ConceptNavi: Mendel & the Gene Idea, three parts
BIOL 1406 Unit Exam IV, Chapter 14, in three short ConceptNavi: Mendel & the Monohybrid Cross, on Mendel’s pea crosses, his four ideas placed on a homologous pair, and Punnett squares and the testcross; The Dihybrid Cross, which follows two genes through meiosis and into the 16-box Punnett square; and Linked Genes & Beyond Mendel, on linkage and crossing over, incomplete dominance, multiple alleles, epistasis, polygenic traits, pleiotropy, the environment and pedigrees. Each ends with a Check Yourself station.
Playable
ConceptNavi: Hormones, three topics
BIOL 1407 Unit Exam III, Chapter 45, in three short ConceptNavi of five stations each: Hormonal Communication, Hormone Polarity & Signal Transduction, and Insect Development & Metamorphosis.
Playable
ConceptNavi: Ovarian & Uterine Cycles
BIOL 1407 Unit Exam III, Chapter 46: six stations on the control chain, the ovarian cycle, the uterine cycle and how they line up, with what-if cases, an Explore mode and a completion card. Open ConceptNavi.
Playable
ConceptNavi: Animal Nutrition, Part 1
BIOL 1407 Unit Exam IV, Chapter 41, Part 1: follow one meal through six stations, from the digestive road map, swallowing and the stomach to digestion and absorption in the small intestine, the large intestine and diet adaptations, and gut microbes and digestive hormones, ending with a Check Yourself station. Open ConceptNavi.
Playable
ConceptNavi: Circulation
BIOL 1407 Unit Exam IV, Chapter 42: five stations on why animals need a circulatory system, one circuit or two, the heart’s chambers, valves and rhythm, blood vessels and blood flow, and blood, clotting and plaque, ending with a Check Yourself station. Open ConceptNavi.
Playable
ConceptNavi: Partial Pressure & Gas Exchange
BIOL 1407 Unit Exam IV, Chapter 42: four stations on the partial pressures of O₂ and CO₂, gas exchange in the lungs and body tissues, and how CO₂ and pH control breathing, ending with a Check Yourself station. Open ConceptNavi.
Playable
ConceptNavi: Osmoregulation & Excretion, two parts
BIOL 1407 Unit Exam IV, Chapter 44, in two short ConceptNavi: Osmoregulation & Nitrogenous Wastes, on osmosis, osmoconformers and osmoregulators, fish in salt and fresh water, salt glands, and ammonia, urea and uric acid; and Excretory Systems & the Kidney, on excretory systems across animals, the nephron, the loop of Henle and the collecting duct, and ADH and the renin–angiotensin–aldosterone system. Each ends with a Check Yourself station.
Playable
ConceptNavi: Innate Immunity, three parts
BIOL 2420 Unit 4A, Chapter 17, in three short ConceptNavi: Barriers & Chemical Defenses, on the lines of defense, physical barriers, resident microbes, lysozyme, interferons, alarm chemicals and complement; Cellular Defense, Blood & Lymphatics, on lymph, blood and hematopoiesis, the leukocytes, NK cells and WBC differentials; and Inflammation, Phagocytosis & Fever, on the cardinal signs, how inflammation ends, phagocytosis, opsonization and fever. Each ends with a Check Yourself station.
In progress
A shared wallet
One balance every game writes to and both worlds read from. Because all of Biosphere lives on one domain, this needs no account and no server.
In progress
Question management for Blackthorn
A way to import question banks and choose which chapter each guardian draws from, so the game can grow with the course instead of being rewritten.
Planned
The Wilds
The role-playing world. Map, encounters, levels and gear, paid for with points from the games.
Planned
The Grove
The village world. A home to earn, furnish and decorate, on no particular schedule.
Planned
More courses, more games
BIOL 1407 has the two chemistry labs and ten ConceptNavi; games on its own topics come next. Faculty who want to contribute one are welcome — a game joins Biosphere by reporting its results in the shared format.